The Stratton kids, Samantha and Chip, and their grandmother, Ada, drive to visit their Uncle Stuart. Grandma collapses and dies in a strange town, leaving the kids and Lassie on their own.
Sally Boyden
Samantha Stratton
John Reilly
Stuart
David Wayne
Amos
Gene Evans
Sheriff Marsh
Lee Bryant
Kathy
Jeff Harlan
Buzz
Jeanette Nolan
Ada Stratton
John McIntire
Dr. Spreckles
Jim Antonio
Mr. Waldrup
Logan Ramsey
Flannagan
Lucille Benson
Juno
Woody Chambliss
Victor Turkey
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